cAMP Gs dynamic kit
Optimal performance when applied to Gs activation or inhibition
PDEs are represented by a large super-family of enzymes whose role is to hydrolyze cAMP into AMP, and cGMP into GMP. It should be emphasized that while not all PDEs lead to the specific hydrolysis of cAMP, the non-selective PDE inhibitor IBMX is often the preferred chemical used in most cAMP accumulation assays.
The use of a Pan-PDE inhibitor ensures that the hydrolysis effect of most PDEs will be inhibited, which in turn guarantees high levels of cAMP accumulation in the cell.
Ultimate guides to master Gs and Gi GPCR assays
Optimizing cAMP assays has never been easier - Guides
Guidelines and recommendations for analyzing GPCR 2nd messenger data
Written by a panel of experts - Guides
HTRF products and supporting scientific content to investifgate GPCRs - Flyers
How HTRF compares to Western Blot and ELISA
Get the brochure about technology comparison. - Brochures
GPCR in Cardiovascular Research: The Relevance of Camp and IP-1 Second Messenger Assays
See how peer researchers monitor GPCR signaling with HTRF - Application Notes
GPCR compounds identification and pharmacological characterization with GTP Gi binding assay
Characterization of candidate molecules through GTP binding assays - Application Notes
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