-->

IBMX Phosphodiesterase inhibitor HTRF®

IBMX is a phosphodiesterase inhibitor to be used in the cAMP Gs and cAMP Gi kits. IBMX guarantees cAMP accumulation in the cytoplasm.
See more
IBMX is a phosphodiesterase inhibitor to be used in the cAMP Gs and cAMP Gi kits. IBMX guarantees cAMP accumulation in the cytoplasm.
-

Overview

PDEs are represented by a large super-family of enzymes whose role is to hydrolyze cAMP into AMP, and cGMP into GMP. It should be emphasized that while not all PDEs lead to the specific hydrolysis of cAMP, the non-selective PDE inhibitor IBMX is often the preferred chemical used in most cAMP accumulation assays.

The use of a Pan-PDE inhibitor ensures that the hydrolysis effect of most PDEs will be inhibited, which in turn guarantees high levels of cAMP accumulation in the cell.

Benefits

  • HIGH PURITY
  • PRODUCED BY MANUFACTURER
  • STRINGENT QUALITY CONTROL

Ultimate guides to master Gs and Gi GPCR assays

Optimizing cAMP assays has never been easier - Guides

Understanding GPCRs is the key to improved DD

In collaboration with GEN - Guides

GPCR research from A to Z

HTRF products and supporting scientific content to investifgate GPCRs - Flyers

HTRF Product Catalog

All your HTRF assays in one document! - Catalog

A guide to Homogeneous Time Resolved Fluorescence

General principles of HTRF - Guides

How HTRF compares to Western Blot and ELISA

Get the brochure about technology comparison. - Brochures

GPCR in Cardiovascular Research: The Relevance of Camp and IP-1 Second Messenger Assays

See how peer researchers monitor GPCR signaling with HTRF - Application Notes

GPCRs Pharmacology

A comprehensive overview of pharmacology's main ligands - Guides

GPCR compounds identification and pharmacological characterization with GTP Gi binding assay

Characterization of candidate molecules through GTP binding assays - Application Notes

GPCRs: the pathway to Discovery

Complete solutions for GPCR Drug Discovery - Brochures

Plate Reader Requirement

Choosing the right microplate reader ensures you’ll get an optimal readout. Discover our high performance reader, or verify if your lab equipment is going to be compatible with this detection technology.

Let's find your reader