cAMP Gs dynamic kit
Optimal performance when applied to Gs activation or inhibition
IBMX Phosphodiesterase inhibitor HTRF®
IBMX is a phosphodiesterase inhibitor to be used in the cAMP Gs and cAMP Gi kits. IBMX guarantees cAMP accumulation in the cytoplasm.
See more
Overview
PDEs are represented by a large super-family of enzymes whose role is to hydrolyze cAMP into AMP, and cGMP into GMP. It should be emphasized that while not all PDEs lead to the specific hydrolysis of cAMP, the non-selective PDE inhibitor IBMX is often the preferred chemical used in most cAMP accumulation assays.
The use of a Pan-PDE inhibitor ensures that the hydrolysis effect of most PDEs will be inhibited, which in turn guarantees high levels of cAMP accumulation in the cell.
Benefits
- HIGH PURITY
- PRODUCED BY MANUFACTURER
- STRINGENT QUALITY CONTROL
Ultimate guides to master Gs and Gi GPCR assays
Optimizing cAMP assays has never been easier - Guides
Understanding GPCRs is the key to improved DD
In collaboration with GEN - Guides
Guidelines and recommendations for analyzing GPCR 2nd messenger data
Written by a panel of experts - Guides
HTRF products and supporting scientific content to investifgate GPCRs - Flyers
All your HTRF assays in one document! - Catalog
A guide to Homogeneous Time Resolved Fluorescence
General principles of HTRF - Guides
How HTRF compares to Western Blot and ELISA
Get the brochure about technology comparison. - Brochures
GPCR in Cardiovascular Research: The Relevance of Camp and IP-1 Second Messenger Assays
See how peer researchers monitor GPCR signaling with HTRF - Application Notes
A comprehensive overview of pharmacology's main ligands - Guides
GPCR compounds identification and pharmacological characterization with GTP Gi binding assay
Characterization of candidate molecules through GTP binding assays - Application Notes
GPCRs: the pathway to Discovery
Complete solutions for GPCR Drug Discovery - Brochures
Plate Reader Requirement
Choosing the right microplate reader ensures you’ll get an optimal readout. Discover our high performance reader, or verify if your lab equipment is going to be compatible with this detection technology.
Let's find your reader
You might be interested in